Lightning McQueen (Owen Wilson) will follow the race to determine the fastest car in the world. Fortunately there are Mater (Larry the Cable Guy) who always helping Lightning to win the race this time.
Lightning must finish the race held in Japan, Germany, Italy, France and England. Each country has a difficult challenge to be faced by Lightning.
Unfortunately, Mater which is expected to help Lightning instead caught in interstate espionage case. Could Lightning won this race? and could Mater complete his mission?